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7 Lifestyle Habits Linked To Reduced Depression Risk

How lifestyle habits impact depression risk and mental health

6 min read
Updated on 
7 Lifestyle Habits Linked To Reduced Depression Risk
MN

Written by Melanie Nolan

BHSc Naturopathy

Melanie is a degree-qualified naturopath, mother of four, and the founder of Naternal Vitamins. She formulated the Naternal range after years of clinical experience helping women through preconception, pregnancy, and postpartum - and after her own frustration with what was available on the supplement shelf. Every article is grounded in clinical research and real-world experience.

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Recent findings 


A balanced lifestyle—including moderate drinking, a nutritious diet, consistent exercise, sufficient sleep, regular social interactions, while avoiding tobacco use and excessive inactivity—plays a critical role in reducing depression risk.


Lifestyle vs. Genetic Predisposition

The most fascinating aspect of recent findings is that, despite genetic predispositions potentially heightening depression susceptibility, lifestyle choices may hold greater significance in mitigating risk.

A study published in Nature Mental Health, conducted by a global team from institutions like the University of Cambridge and Fudan University, explored the interplay between lifestyle habits, genetic factors, brain structure, immunological and metabolic functions, and their links to depression.


Global Impact of Depression

Depression affects approximately 5% of adults worldwide, posing a significant public health challenge. Its triggers are complex, involving both biological and lifestyle elements.

The study utilized the UK Biobank's extensive database, analyzing nearly 290,000 participants over nine years, identifying seven lifestyle habits linked to reduced depression risk:

  1. Moderate drinking

  2. Nutritious eating

  3. Regular exercise

  4. Adequate sleep

  5. Non-smoking

  6. Limited sedentary time

  7. Regular social engagement

The Most Effective Lifestyle Habits

Among these, optimal sleep—seven to nine hours nightly—was most effective, lowering depression risk by 22%!

Additionally:

  • Social engagement significantly protected against recurrent depressive disorders, reducing risk by 18%.

  • Moderate drinking cut depression risk by 11%.

  • A healthy diet reduced risk by 6%.

  • Regular exercise lowered risk by 14%.

  • Abstaining from smoking decreased risk by 20%.

  • Minimal sedentary behaviour reduced risk by 13%.


Categorization of Participants Based on Lifestyle

Participants were grouped based on lifestyle habits into unfavourable, intermediate, and favourable categories:

  • The intermediate category had a 41% lower depression risk compared to the unfavourable group.

  • The favourable group experienced a 57% reduction in depression risk.

Genetic Predisposition and Depression Risk

The study also examined genetic predispositions, assigning participants a genetic risk score based on depression-linked genetic variants. Findings showed:

  • Those with a lower genetic risk were 25% less likely to develop depression compared to high-risk individuals.

  • Lifestyle habits had a more substantial impact than genetic factors in reducing depression risk.


Further investigation into why healthy living lowers depression risk revealed certain brain regions, like the pallidum and hippocampus, were larger and potentially more robust in those leading healthier lifestyles. Blood markers also suggested that lifestyle influences immune and metabolic health, which in turn affects depression risk.