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Naternal Vitamins

Naternal Vitamins

When Iron "Within Range"
Isn't Enough

Ferritin below 50 µg/L is not always physiologically optimal — even if it sits inside laboratory reference intervals.

Why Ferritin Matters

Ferritin is the primary marker of iron storage. But "within range" does not always mean physiologically adequate. Many laboratory reference intervals start as low as 15 µg/L — a threshold that reflects statistical population norms, not optimal function.

A ferritin below 50 µg/L is not always physiologically optimal — even when a lab report says "normal". Symptoms such as fatigue, brain fog, breathlessness, restless legs, and hair loss frequently persist at levels conventional medicine considers acceptable.

If your ferritin sits between 15 and 50 µg/L and you've been told 'everything looks fine' — your symptoms are not imagined. Your body is asking for more.

Deficient

< 15 µg/L

Iron stores depleted. Symptoms likely present.

Low

15-30 µg/L

Suboptimal stores. Fatigue, hair loss, poor recovery common.

"Normal" but not optimal

30-50 µg/L

Within range — but many women remain symptomatic here.

Functionally adequate

50-100 µg/L

Where most women begin to feel meaningfully better.

Optimal

100-200 µg/L

Robust stores. Energy, cognition, and exercise tolerance supported.

LETS TALK IRON LEVELS

Iron Physiology: Why So Many Women Have Low Iron

Iron metabolism is tightly regulated.

Absorption occurs primarily in the duodenum. Once absorbed, iron is:

  • Transported via transferrin
  • Stored as ferritin
  • Incorporated into haemoglobin and myoglobin
  • Utilised in mitochondrial energy production

But absorption is not passive.

It is regulated by hepcidin, a hepatic peptide hormone that controls intestinal iron uptake.

Hepcidin and Oral Iron

Following an oral iron dose, hepcidin increases for approximately 24 hours, reducing subsequent absorption.

Moretti et al., 2017 (The Lancet Haematology) demonstrated that alternate-day dosing resulted in significantly higher fractional iron absorption compared with consecutive daily dosing in iron-depleted women.

More iron does not equal more absorption.
Strategic dosing matters.

Iron Form Matters

Conventional iron salts (e.g. ferrous sulfate, ferrous fumarate) are effective but frequently associated with:

  • Gastrointestinal irritation linked to microbiome composition changes
  • Nausea
  • Constipation
  • Poor compliance

Ferrous bisglycinate (Ferrochel®) is a chelated form in which iron is bound to glycine. Clinical comparisons suggest improved gastrointestinal tolerability and superior bioavailability.

Naternal Vitamins

Practitioner Formulated

IronBiotic

IronBiotic is a gentle, vegan iron supplement formulated with highly absorbable iron bisglycinate and a probiotic to support healthy iron levels and energy — without digestive discomfort.

  • Iron bisglycinate — highly absorbable and gentle
  • Includes Bifidobacterium longum to support digestive health
  • Vitamin C to enhance iron absorption
  • Activated B-vitamins for red blood cell production
  • Includes copper and beta carotene

Ironbiotic Provides

120mg Ferrochel®
Equivalent to 24mg elemental iron

Equivalent to 24mg elemental iron

A dose selected to balance efficacy with tolerability and absorption dynamics.

Naternal Vitamins

Hero Ingredients

The Full Formula Explained —
Every Ingredient Has a Role

Vitamin C (Magnesium Ascorbate – 100mg)

Ascorbic acid enhances non-heme iron absorption by reducing ferric iron (Fe³⁺) to the more absorbable ferrous form (Fe²⁺). Magnesium ascorbate provides vitamin C in a buffered form to minimise gastric irritation.

This is included not for marketing – but for mechanism.

Copper: The Overlooked Co-Factor

Copper-dependent enzymes such as ceruloplasmin and hephaestin are required for iron mobilisation and incorporation into transferrin. Copper deficiency can impair iron transport and contribute to iron-deficiency.

IronBiotic includes Copper gluconate – equivalent to 1.5mg copper. This supports the full iron utilisation pathway rather than focusing on iron in isolation.

B Vitamins and Erythropoiesis

Iron deficiency fatigue is not solely about haemoglobin concentration. Red blood cell production requires coordinated support from multiple nutrients. If you correct iron but neglect co-factors, symptom resolution may lag.

  •  
    Methyl-folate (Quatrefolic® – 200mcg active 5-MTHF)
  •  
    Methylcobalamin (B12 – 400mcg)
  •  
    P5P (active B6)
  •  
    Riboflavin-5-phosphate
  •  
    Thiamine
  •  
    Niacinamide
  •  
    Pantothenic acid
  •  
    Biotin
Bifidobacterium longum (500 million CFU)

Iron supplementation can alter gut microbiota composition and contribute to dysbiosis-related symptoms. Bifidobacterium longum is included to support gastrointestinal balance and improve tolerability.

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